CF202648817
Ph.D. scholarship - PFAS transfer in ruminants: from animal experiments to computational models
J-29
Doctorat
Agronomie Ecologie
Disciplines
Laboratoire
Institution d'accueil

Description

This is how you can contribute


Planification and execution of toxicokinetic animal experiments
Coordination of sample preparation and analytical workflow integration
Data management, statistical analyses and interpretation
Evaluation of physiologically based toxicokinetic (PBTK) models of PFAS fate in ruminants
Communication and publication of results in scientific journals, scientific reporting for funders and stakeholders
Project management and collaboration within an international consortium


In a nutshell

Per- and polyfluoroalkyl substances (PFAS), commonly referred to as “forever chemicals”, are highly persistent compounds that are easily dispersed in the environment and bioaccumulate along the food chain, posing major environmental and public health challenges worldwide. In Switzerland, the recent discovery of PFAS contamination in agricultural areas raises growing public concern and highlights the urgent need to better understand exposure pathways, transfer within livestock systems, and mitigation options to protect food safety.

Within this context, the PhD candidate will contribute to the research project “PFArmS – Assessment and mitigation of the transfer of per- and polyfluoroalkyl substances (PFAS) in ruminants”. Positioned at the interface of environmental and animal sciences, toxicokinetics, and food safety, the project aims to elucidate and reduce PFAS exposure and transfer in ruminant husbandry systems. The PhD candidate will focus on PFAS toxicokinetics in cattle and sheep, combining controlled animal experiments with strategies to enhance PFAS depuration and physiologically based toxicokinetic (PBTK) modeling, to support evidence-based mitigation measures along the feed-to-food chain.

You have a background in animal or veterinary science, pharmacology, toxicology, biology, bioinformatics or a related interdisciplinary field, with a strong interest in applied research and chemical food safety. You are interested in animal nutrition, physiology, and in how contaminants like PFAS behave within biological systems. You are interested in combining practical experimental methods with computational methods. You have very good computer skills and some experience in handling data and models, as well as scientific writing skills, along with motivation to further develop these skills.

PFArmS is conducted within a strong research network involving Agroscope, Empa (Dübendorf, Switzerland), and the German Federal Institute for Risk Assessment (BfR, Berlin), offering an interdisciplinary and applied research environment at the interface of environmental science, animal science, and food safety.

Additional information

The 'Ruminant Nutrition and Emissions' Research Group is represented at the Posieux and Tänikon sites. We deal with ruminant physiology, nutrition and husbandry in roughage-focused feeding systems with the aim of sustainably improving nutrient efficiency, lowering emissions from cattle husbandry, reducing nutrient-related production diseases, and maintaining high product quality.

Offre financée

Type de financement
Contrat Doctoral

Dates

Date limite de candidature 09/07/26

Date de création12/05/26

Langues

Niveau de français requis

Niveau d'anglais requis

Divers

Frais de scolarité annuels € / an

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