Description

See attached file.

Skills required

Highly motivated student, holding a Master in chemistry (major in organic chemistry). The applicant will be familiar with all analytical methods to determine organic structures (NMR, Mass spectroscopy). Excellent theoretical and practical skills in Modern Synthetic Organic Chemistry are required.

Bibliography

1. “[2,3]-Sigmatropic Rearrangement of Ynamides: Preparation of α-Amino Allenephosphonates.” Gomes, F.; Fadel, A.; Rabasso, N. J. Org. Chem. 2012, 77, 5439–5444.
2. “Selective Reduction of Amino Allenephosphonates: Preparation of α-Amino Vinylphosphonates.” Adler, P.; Gomes, F.; Fadel, A.; Rabasso, N. Eur. J. Org. Chem. 2013, 7546–7555.
3. “Strategies for the synthesis of α- and β-amino vinylphosphonate.” Adler, P.; Fadel, A.; Rabasso, N. Tetrahedron 2014, 70, 4437–4456.
4. “From acyclic to cyclic α-amino vinylphosphonates by using ring-closing metathesis” Adler, P.; Fadel, A.; Prunet, J.; Rabasso, N. Org. Biomol. Chem. 2017, 15, 387-395.
5. “Cerium(IV) ammonium nitrate mediated 5-endo-dig cyclization of α-amino allenylphosphonates to spirodienones.” Adler, P.; Fadel, A.; Rabasso, N. Chem. Commun. 2015, 51, 3612–3615.
6. “Synthesis of N-Sulfonyl Ynamido-Phosphonates: Valuable Partners for Cycloadditions.” Perez, V.; Fadel, A.; Rabasso, N. Synthesis, 2017, 49, 4035-4044

Keywords

organic chemistry, enamines, cycloaddition, redox photocatalysis